SNPMiner Trials by Shray Alag


SNPMiner Trials: Clinical Trial Report


Report for Clinical Trial NCT00780949

Developed by Shray Alag, 2019.
SNP Clinical Trial Gene

Immunological Consequences of CARD15/NOD2 Mutations in Crohn's Disease

The project is based on adult and paediatric cohorts among the largest ones in Paris and located at Saint Louis and Robert Debré hospitals. Experiments will be performed at INSERM Unit U843 in collaboration with the department of immunology and statistics, Robert Debré Hospital.

NCT00780949 Crohn's Disease
MeSH: Crohn Disease
HPO: Crohn's disease

1 Interventions

Name: intestinal biopsies

Description: intestinal biopsies during routine endoscopy

Type: Other

1: Crohn's disease patient


Primary Outcomes

Measure: cytokine production and cell phenotype in Peyer patches

Time: final time frame at the end of the study

Purpose: Basic Science

Single Group Assignment


There are 2 SNPs

SNPs


1 G908R

The aim of the present proposal is to better understand the role of CARD15/NOD2 mutations (R702W, G908R and 1007fs) in the development and the function of the intestinal lymphoid tissue. --- R702W --- --- G908R ---


2 R702W

The aim of the present proposal is to better understand the role of CARD15/NOD2 mutations (R702W, G908R and 1007fs) in the development and the function of the intestinal lymphoid tissue. --- R702W ---



HPO Nodes


HPO:
Crohn's disease
Genes 2
IGHM PSTPIP1