SNPMiner Trials by Shray Alag


SNPMiner Trials: Clinical Trial Report


Report for Clinical Trial NCT00160888

Developed by Shray Alag, 2019.
SNP Clinical Trial Gene

Endothelium-Dependent Vasoreactivity in Nitric Oxide Synthase Gene (Glu298Asp) Polymorphism: Studies in Healthy Volunteers

The objective of the study is to assess the impact of genetic variation (especially polymorphisms of the gene coding endothelial nitric oxide synthase (eNOS) and the bradykinin B2 receptor gene) on venous and arterial responsiveness to vasodilators in healthy individuals without cardiovascular risk factors.

NCT00160888 Healthy

1 Interventions

Name: sodium nitroprusside, bradykinin, acetylcholine

Type: Drug


Primary Outcomes

Measure: Study I: Venous responsiveness assessed by dorsal hand vein compliance technique

Measure: Study II: Forearm blood flow assessed by venous occlusion plethysmography

Purpose: Educational/Counseling/Training

Allocation: Non-Randomized

Single Group Assignment


There is one SNP

SNPs


1 E298D

Endothelium-Dependent Vasoreactivity in Nitric Oxide Synthase Gene (Glu298Asp) Polymorphism: Studies in Healthy Volunteers. --- Glu298Asp ---



HPO Nodes