This 48 week study is designed to compare the substitution of the thymidine analogues zidovudine (ZDV) or stavudine (D4T) with either tenofovir DF or abacavir, in patients treated with highly active antiretroviral therapy (HAART), and show improved outcomes on total limb fat mass, improved body shape by dual energy x-ray absorptiometry (DEXA) and computed tomography (CT) scans and improved cholesterol and tryglicerides.
Name: tenofovir disoproxil fumarateType: Drug
Name: AbacavirType: Drug
There is one SNP
Subjects with no known K65R, 69S mutations or 3 or more thymidine analogue mutations. --- K65R ---