The study is aimed at assessing the influence of two betaine doses (2.5 g∙d-1 and 5 g∙d-1) supplemented for three weeks in a group of speed-strength trained athletes on anaerobic capacity in Wingate test, performance in CrossFit-like exercise test - Fight Gone Bad, alterations in body compositions and total body water.
Name: Betaine supplementation
Description: Group taking oral betaine supplementationType: Dietary SupplementBetaine supplementation Placebo treatment
Name: Placebo treatment
Description: Group taking oral supplementation with placebo (starch) in a similar capsule form.Type: Dietary SupplementBetaine supplementation Placebo treatment
Description: Fat mass (kg) and fat free mass (kg) analysis
Measure: Changes in fat mass and fat free mass after betaine supplementation Time: Baseline and after 3 weeksDescription: The Wingate cycling test (W)
Measure: Changes in anaerobic capacity after betaine supplementation Time: Baseline and after 3 weeksDescription: The CrossFit-specific physical fitness test: Fight Gone Bad (reps.)
Measure: Changes in specific performance capacity after betaine supplementation Time: Baseline and after 3 weeksDescription: Total body water content (%)
Measure: Changes in total body water after betaine supplementation Time: Baseline and after 3 weeksDescription: Testosterone level (ng/L)
Measure: Changes in testosterone level (ng/L) after betaine supplementation Time: Baseline and after 3 weeksDescription: Amino acid profile (μmol/L)
Measure: Changes in amino acid profile after betaine supplementation Time: Baseline and after 3 weeksDescription: Blood betaine (µmol/L)
Measure: Changes in blood betaine Time: Baseline and after 3 weeksDescription: Total, LDL and HDL cholesterol (mg/dL) and triacylglycerol (mg/dL)
Measure: Changes in total, LDL and HDL cholesterol and triacylglycerol after betaine supplementation Time: Baseline and after 3 weeksDescription: MTHFR (rs1801133) polymorphism
Measure: Difference in response to betaine supplementation depending on MTHFR (rs1801133) polymorphism Time: Baseline and after 3 weeksAllocation: Randomized
Crossover Assignment
There is one SNP
Difference in response to betaine supplementation depending on MTHFR (rs1801133) polymorphism.
MTHFR (rs1801133) polymorphism.